Cytotoxicity, and antimicrobial and physicochemical properties of sealers incorporated with Uncaria tomentosa

This study evaluated the cytotoxicity, antimicrobial and physicochemical properties of root canal sealers incorporated with phytotherapic Uncaria tomentosa (UT). Unmodified AH Plus (Dentsply, DeTrey, Germany) MTA Fillapex (Angelus, Londrina, Brazil) were used as controls. UT was into Fillapex, at concentrations 2% 5% total weight these (w/w). Flowability, setting time, solubility following ISO requirements. The pH values measured periods 12, 24, 48 hours, 7 days. activity against Enterococcus faecalis analyzed by both direct contact tests in freshly prepared sealers, after cytotoxicity samples MTT assay, to check Balb/c 3T3 cell viability. statistical analysis performed one-way ANOVA Tukey's test (p < 0.05). incorporation associated a decrease flow, for an increase values, (after 14 days), Regarding antibacterial evaluation, bacterial reduction reported up days handling material (P<0.05). decreased cytotoxic effects way directly proportional their respective In conclusion, can be added reduce improve effects, without compromising original properties.